Coding strategy differences between constant and variable segments of immunoglobulin genes
نویسندگان
چکیده
منابع مشابه
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. 1976 [classical article].
A high-molecular-weight DNA from Balb/c mouse early embryo or from MOPC 321 plasmacytoma (a k-chain producer) was digested to completion with Bacillus amyloliquefaciens strain H restriction enzyme (BamH I). The resulting DNA fragments were fractionated according to size in preparative agarose gel electrophoresis. DNA fragments carrying gene sequences coding for the variable or constant region o...
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The mechanism of generating immunoglobulin light chain genes by rearrangement of variable (V), joining (J), and constant (C) gene segments is still unknown. It has been discussed mostly in terms of excision and deletion of the DNA between the recombined V and J gene segments. However, the finding of DNA digests from the mouse myeloma T of a fragment (called f-T) that contains the 3' flank of a ...
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The 'Mouse (Mus musculus) Immunoglobulin Kappa Variable (IGKV) Genes and Joining (IGKJ) Segments', third report of the 'IMGT Locus on Focus' section, comprises four tables entitled: (1) 'Mouse (Mus musculus) germline IGKV gene table'; (2) 'Correspondence between Mouse (Mus musculus) IMGT IGKV subgroups and previous designations'; (3) 'Mouse (Mus musculus) germline IGKJ table', and (4) 'Mouse (M...
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The first report of the 'IMGT Locus on Focus' section comprises five tables entitled: (1) 'Number of human germline IGLV genes at 22q11.1-q11.2 and potential repertoire'; (2) 'Human germline IGLV gene table'; (3) 'Human IGLV allele table', (4) 'Human germline IGLJ table' and (5) 'Human IGLJ allele table'. These tables are available at the MariePaule page from IMGT, the international ImMunoGeneT...
متن کاملThe human immunoglobulin kappa variable (IGKV) genes and joining (IGKJ) segments.
'Human Immunoglobulin Kappa Variable (IGKV) Genes and Joining (IGKJ) Segments', second report of the 'IMGT Locus on Focus' section, comprises five tables entitled: (1) 'Number of human germline IGKV genes at 2p12 and potential repertoire'; (2) 'Human germline IGKV gene table'; (3) 'Human IGKV allele table'; (4) 'Human germline IGKJ table' and (5) 'Human IGKJ allele table'. These tables are avai...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1984
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/12.13.5515